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Article

Dimensionality of genomic information and its impact on genome-wide associations and variant selection for genomic prediction: a simulation study.

Genetics, selection, evolution : GSE - 17 Jul 2023

Jang Sungbong, Tsuruta Shogo, Leite Natalia Galoro, Misztal Ignacy, Lourenco Daniela

Abstract excerpt

BACKGROUND: Identifying true positive variants in genome-wide associations (GWA) depends on several factors, including the number of genotyped individuals. The limited dimensionality of genomic information may give insights into the optimal number of individuals to be used in GWA. This study investigated different discovery set sizes based on the number of largest eigenvalues explaining a certain proportion of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37460964
DOI: 10.1186/s12711-023-00823-0
PMCID: PMC10351171

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