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Improved individual identification in DNA mixtures of unrelated or related contributors through massively parallel sequencing.

Forensic science international. Genetics - 1 Sept 2024

Liu Zhiyong, Wu Enlin, Li Ran, Liu Jiajun, Zang Yu, Cong Bin, Wu Riga, Xie Bo, Sun Hongyu

Abstract excerpt

DNA mixtures are a common sample type in forensic genetics, and we typically assume that contributors to the mixture are unrelated when calculating the likelihood ratio (LR). However, scenarios involving mixtures with related contributors, such as in family murder or incest cases, can also be encountered. Compared to the mixtures with unrelated contributors, the kinship within the mixture would bring additional...

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PMID: 38889491
DOI: 10.1016/j.fsigen.2024.103078

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