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Article

Adenine nucleotide carrier protein dysfunction in human disease.

IUBMB life - 1 Nov 2023

Mishra Gargi, Coyne Liam P, Chen Xin Jie

Abstract excerpt

Adenine nucleotide translocase (ANT) is the prototypical member of the mitochondrial carrier protein family, primarily involved in ADP/ATP exchange across the inner mitochondrial membrane. Several carrier proteins evolutionarily related to ANT, including SLC25A24 and SLC25A25, are believed to promote the exchange of cytosolic ATP-Mg2+ with phosphate in the mitochondrial matrix. They allow a net accumulation of...

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PMID: 37449547
DOI: 10.1002/iub.2767
PMCID: PMC10592433

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