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Article

Molecular diagnosis of patients with hepatitis A virus infection using amplicon-based nanopore sequencing.

PloS one - 1 Jan 2023

Lee Geum-Young, Park Kyungmin, Lee Young-Sun, Kim Ji Hoon, Byun Kwan Soo, Kim Jongwoo, Kim Won-Keun, Song Jin-Won

Abstract excerpt

High-throughput sequencing is a robust tool used for identifying and tracking pathogen outbreaks. Whole-genome sequencing of hepatitis A virus (HAV) remains poor due to ultra-low viral loads, limitations of next-generation sequencing technology, and its high costs in clinical applications. This study evaluated multiplex polymerase chain reaction (PCR)-based nanopore sequencing to obtain whole-genome sequences of...

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Identifiers

PMID: 37437048
DOI: 10.1371/journal.pone.0288361
PMCID: PMC10337952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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