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Article

Development and Evaluation of a Molecular Hepatitis A Virus Assay for Serum and Stool Specimens.

Viruses - 15 Jan 2022

Kozak Robert A, Rutherford Candace, Richard-Greenblatt Melissa, Chau N Y Elizabeth, Cabrera Ana, Biondi Mia, Borlang Jamie, Day Jaqueline, Osiowy Carla, Ramachandran Sumathi, Mayer Nancy, Glaser Laurel, Smieja Marek

Abstract excerpt

Hepatitis A virus (HAV) is an emerging public health concern and there is an urgent need for ways to rapidly identify cases so that outbreaks can be managed effectively. Conventional testing for HAV relies on anti-HAV IgM seropositivity. However, studies estimate that 10-30% of patients may not be diagnosed by serology. Molecular assays that can directly detect viral nucleic acids have the potential to improve...

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Identifiers

PMID: 35062362
DOI: 10.3390/v14010159
PMCID: PMC8777614

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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