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Article

Genome Editing and Cardiac Arrhythmias

11 May 2023

Abstract excerpt

This article reviews progress in the field of cardiac genome editing, in particular, its potential utility in treating cardiac arrhythmias. First, we discuss genome editing methods by which DNA can be disrupted, inserted, deleted, or corrected in cardiomyocytes. Second, we provide an overview of in vivo genome editing in preclinical models of heritable and acquired arrhythmias. Third, we discuss recent...

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PMID: 37408197
DOI: 10.3390/cells12101363

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