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Gene Editing Applications as Future Cardiovascular Therapies

16 Jul 2025

Abstract excerpt

Cardiovascular disease is the leading cause of global morbidity and mortality, despite advances in pharmacological and surgical interventions. The emergence of CRISPR-Cas9 genome editing technology offers promising approaches for correcting genetic causes of hereditary cardiovascular disorders and modulating pathogenic signaling pathways implicated in various heart diseases. However, several challenges with...

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PMID: 40669499
DOI: 10.1146/annurev-genet-011725-094039

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