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Hypoferremia of inflammation: Innate host defense against infections

21 Jun 2023

Abstract excerpt

Iron is an essential nutrient for microbes, plants and animals. Multicellular organisms have evolved multiple strategies to control invading microbes by restricting microbial access to iron. Hypoferremia of inflammation is a rapidly-acting organismal response that prevents the formation of iron species that would be readily accessible to microbes. This review takes an evolutionary perspective to explore the...

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PMID: 37391347
DOI: 10.1016/j.bcmd.2023.102777

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