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Article

Non-coding variants in VAMP2 and SNAP25 affect gene expression: potential implications in migraine susceptibility.

The journal of headache and pain - 29 Jun 2023

Felício Daniela, Dias Andreia, Martins Sandra, Carvalho Estefânia, Lopes Alexandra M, Pinto Nádia, Lemos Carolina, Santos Mariana, Alves-Ferreira Miguel

Abstract excerpt

Migraine is a common and complex neurological disease potentially caused by a polygenic interaction of multiple gene variants. Many genes associated with migraine are involved in pathways controlling the synaptic function and neurotransmitters release. However, the molecular mechanisms underpinning migraine need to be further explored.Recent studies raised the possibility that migraine may arise from the effect...

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Source

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Identifiers

PMID: 37380951
DOI: 10.1186/s10194-023-01615-z
PMCID: PMC10308609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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