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Article

Recombinant lysyl oxidase effects on embryonic tendon cell phenotype and behavior.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Oct 2023

Nguyen Phong K, Hall Kaitlyn, Holt Iverson, Kuo Catherine K

Abstract excerpt

Lysyl oxidase (LOX) plays an important role in the elaboration of tendon mechanical properties during embryonic development by mediating enzymatic collagen crosslinking. We previously showed recombinant LOX (rLOX) treatment of developing tendon significantly increased LOX-mediated collagen crosslink density to enhance tendon mechanical properties at different stages of tissue formation. Working toward the future...

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Identifiers

PMID: 37365857
DOI: 10.1002/jor.25655
PMCID: PMC11487497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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