Article
Resting heart rate and antisocial behaviour: a Mendelian randomisation study.
Scientific reports - 23 Jun 2023
Karwatowska Lucy, Frach Leonard, Schoeler Tabea, Tielbeek Jorim J, Murray Joseph, de Geus Eco, Viding Essi, Pingault Jean-Baptiste
Abstract excerpt
Observational studies frequently report phenotypic associations between low resting heart rate (RHR) and higher levels of antisocial behaviour (ASB), although it remains unclear whether this relationship reflects causality. To triangulate evidence, we conducted two-sample univariable Mendelian randomisation (MR), multivariable MR and linkage disequilibrium score regression (LDSC) analyses. Genetic data were...
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