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Article

Development of a Systems Medicine Approach to Spinal Cord Injury.

Journal of neurotrauma - 1 Sept 2023

Guest James D, Kelly-Hedrick Margot, Williamson Theresa, Park Christine, Ali Daniyal Mansoor, Sivaganesan Ahilan, Neal Chris J, Tator Charles H, Fehlings Michael G

Abstract excerpt

Traumatic spinal cord injury (SCI) causes a sudden onset multi-system disease, permanently altering homeostasis with multiple complications. Consequences include aberrant neuronal circuits, multiple organ system dysfunctions, and chronic phenotypes such as neuropathic pain and metabolic syndrome. Reductionist approaches are used to classify SCI patients based on residual neurological function. Still, recovery...

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Identifiers

PMID: 37335060
DOI: 10.1089/neu.2023.0024
PMCID: PMC10460697

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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