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Article

USP33 promotes pancreatic cancer malignant phenotype through the regulation of TGFBR2/TGFβ signaling pathway.

Cell death & disease - 15 Jun 2023

Liu Xinyuan, Xu Jian, Shen Bingbing, Xu Jichuan, Jiang Jianxin

Abstract excerpt

Pancreatic cancer (PC) ranked fourth among cancer-related death worldwide with a survival rate less than 5%. The abnormal proliferation and distant metastasis are major obstacles for the diagnosis and treatment of pancreatic cancer, therefore, it is urgent for researchers to uncover the molecular mechanisms underlying the PC proliferation and metastasis. In current study, we found that USP33, a member of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37322017
DOI: 10.1038/s41419-023-05871-4
PMCID: PMC10272277

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