Article
Lack of significant associations between single nucleotide polymorphisms in LPAL2-LPA genetic region and all cancer incidence and mortality in Japanese population: The Japan public health center-based prospective study.
Cancer epidemiology - 1 Aug 2023
Mieno Makiko Naka, Yamasaki Maria, Kuchiba Aya, Yamaji Taiki, Ide Keigo, Tanaka Noriko, Sawada Norie, Inoue Manami, Tsugane Shoichiro, Sawabe Motoji, Iwasaki Motoki
Abstract excerpt
BACKGROUND: High lipoprotein (a) level is an established cardiovascular risk, but its association with non-cardiovascular diseases, especially cancer, is controversial. Serum lipoprotein (a) levels vary widely by genetic backgrounds and are largely determined by the genetic variations of apolipoprotein (a) gene, LPA. In this study, we investigate the association between SNPs in LPA region and cancer incidence and...
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