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Article

Negative correlation between acetyl-CoA acyltransferase 2 and cetuximab resistance in colorectal cancer.

Acta biochimica et biophysica Sinica - 13 Jun 2023

Yuan Yitao, Sun Xun, Liu Mengling, Li Suyao, Dong Yu, Hu Keshu, Zhang Jiayu, Xu Bei, Ma Sining, Jiang Hesheng, Hou Pengcong, Lin Yufu, Gan Lu, Liu Tianshu

Abstract excerpt

The emergence of anti-EGFR therapy has revolutionized the treatment of colorectal cancer (CRC). However, not all patients respond consistently well. Therefore, it is imperative to conduct further research to identify the molecular mechanisms underlying the development of cetuximab resistance in CRC. In this study, we find that the expressions of many metabolism-related genes are downregulated in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37310146
DOI: 10.3724/abbs.2023111
PMCID: PMC10520478

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