Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of genotype on the phenotype of Mycobacterium tuberculosis ΔsufR mutants.

Tuberculosis (Edinburgh, Scotland) - 1 Jul 2023

Willemse Danicke, Baatjies Lucinda, Dippenaar Anzaan, Warren Robin M, Williams Monique J

Abstract excerpt

Iron-sulphur (FeS) cluster biogenesis is a tightly regulated process in vivo. In Mycobacterium tuberculosis (Mtb), SufR functions as a transcriptional repressor of the operon encoding the primary FeS cluster biogenesis system. Previously, three independently isolated mutants (ΔRv1460stop_1.19, ΔRv1460stop _5.19 and ΔRv1460stop _5.20) harbouring the same deletion in sufR, displayed different growth kinetics in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Genotype
Share to Iron-Sulfur Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mycobacterium tuberculosis

Share to Phenotype

Source

Identifiers

PMID: 37295353
DOI: 10.1016/j.tube.2023.102360

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

The impact of genotype on the phenotype of Mycobacterium tuberculosis ΔsufR mutants.PMID 37295353Read ↗

Rv1460, a SufR homologue, is a repressor of the suf operon in Mycobacterium tuberculosis.Semantic proximity Read ↗

The reduced interaction between SufS and SufU in Mycoplasma penetrans results in diminished sulfotransferase activity.Semantic proximity Read ↗

Cysteine desulfurase (IscS)–mediated fine-tuning of bioenergetics and SUF expression prevents Mycobacterium tuberculosis hypervirulenceSemantic proximity Read ↗

Functional genomics reveals the sole sulphate transporter of the Mycobacterium tuberculosis complex and its relevance to the acquisition of sulphur in vivo.Semantic proximity Read ↗

Comprehensive analysis of iron utilization by Mycobacterium tuberculosis.Semantic proximity Read ↗

Genotypic and phenotypic diversity of Mycobacterium tuberculosis complex genotypes prevalent in West Africa.Semantic proximity Read ↗

Genome scale CRISPRi reveals both shared and strain-specific vulnerabilities in genetically diverse drug-resistant strains of Mycobacterium tuberculosis.Semantic proximity Read ↗

Genome mining of Mycobacterium tuberculosis: targeting SufD as a novel drug candidate through in silico characterization and inhibitor screeningSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.