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BCL11B expression in hepatocellular carcinoma relates to chemosensitivity and clinical prognosis

9 Jun 2023

Abstract excerpt

INTRODUCTION: B-cell lymphoma/leukemia 11B (BCL11B) is a subunit of SWI/SNF chromatin remodeling complexes and functions in cell cycle regulation and apoptosis upon DNA replication stress and damages via transcription. Many malignancies were reported to exhibit changes in BCL11B gene expression; however, no study has focused on the relationship between BCL11B and hepatocellular carcinoma, which potentially...

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PMID: 37293953
DOI: 10.1002/cam4.6167

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