Article
Rheumatoid arthritis increases the risk of heart failure-current evidence from genome-wide association studies.
Frontiers in endocrinology - 1 Jan 2023
Wang Min, Mei Kun, Chao Ce, Di Dongmei, Qian Yongxiang, Wang Bin, Zhang Xiaoying
Abstract excerpt
Background: Numerous studies have demonstrated that rheumatoid arthritis (RA) is related to increased incidence of heart failure (HF), but the underlying association remains unclear. In this study, the potential association of RA and HF was clarified using Mendelian randomization analysis. Methods: Genetic tools for RA, HF, autoimmune disease (AD), and NT-proBNP were acquired from genome-wide studies without...
Topics
- Humans
- Genome-Wide Association Study
- Genetic Predisposition to Disease
- Reproducibility of Results
- Arthritis, Rheumatoid
- Heart Failure