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In silico Screening and Validation of Achyranthes aspera as a Potential Inhibitor of BRAF and NRAS in Controlling Thyroid Cancer.

Anti-cancer agents in medicinal chemistry - 1 Jan 2023

Alamri Ahmad M, Alkhilaiwi Faris A, Khan Najeeb U, Tasleem Munazzah

Abstract excerpt

BACKGROUND: Thyroid carcinoma (THCA) is one of the most prevalent endocrine tumors, accounting for 3.4% of all cancers diagnosed annually. Single Nucleotide Polymorphisms (SNPs) are the most prevalent genetic variation associated with thyroid cancer. Understanding thyroid cancer genetics will enhance diagnosis, prognosis, and treatment. METHODS: This TCGA-based study analyzes thyroid cancer-associated highly...

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PMID: 37287303
DOI: 10.2174/1871520623666230607125258

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