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Article

Individual-specific functional connectivity improves prediction of Alzheimer's disease's symptoms in elderly people regardless of APOE ε4 genotype.

Communications biology - 31 May 2023

Hua Lin, Gao Fei, Xia Xiaoluan, Guo Qiwei, Zhao Yonghua, Huang Shaohui, Yuan Zhen

Abstract excerpt

To date, reliable biomarkers remain unclear that could link functional connectivity to patients' symptoms for detecting and predicting the process from normal aging to Alzheimer's disease (AD) in elderly people with specific genotypes. To address this, individual-specific functional connectivity is constructed for elderly participants with/without APOE ε4 allele. Then, we utilize recursive feature selection-based...

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Identifiers

PMID: 37258640
DOI: 10.1038/s42003-023-04952-6
PMCID: PMC10232409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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