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A peripheral signature of Alzheimer’s disease featuring microbiota-gut-brain axis markers

31 May 2023

Abstract excerpt

BACKGROUND: Increasing evidence links the gut microbiota (GM) to Alzheimer's disease (AD) but the mechanisms through which gut bacteria influence the brain are still unclear. This study tests the hypothesis that GM and mediators of the microbiota-gut-brain axis (MGBA) are associated with the amyloid cascade in sporadic AD. METHODS: We included 34 patients with cognitive impairment due to AD (CI-AD), 37 patients...

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PMID: 37254223
DOI: 10.1186/s13195-023-01218-5

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