Article
Candidate SNP Markers Significantly Altering the Affinity of TATA-Binding Protein for the Promoters of Human Hub Genes for Atherogenesis, Atherosclerosis and Atheroprotection.
International journal of molecular sciences - 19 May 2023
Bogomolov Anton, Filonov Sergey, Chadaeva Irina, Rasskazov Dmitry, Khandaev Bato, Zolotareva Karina, Kazachek Anna, Oshchepkov Dmitry, Ivanisenko Vladimir A, Demenkov Pavel, Podkolodnyy Nikolay, Kondratyuk Ekaterina, Ponomarenko Petr, Podkolodnaya Olga, Mustafin Zakhar, Savinkova Ludmila, Kolchanov Nikolay, Tverdokhleb Natalya, Ponomarenko Mikhail
Abstract excerpt
Atherosclerosis is a systemic disease in which focal lesions in arteries promote the build-up of lipoproteins and cholesterol they are transporting. The development of atheroma (atherogenesis) narrows blood vessels, reduces the blood supply and leads to cardiovascular diseases. According to the World Health Organization (WHO), cardiovascular diseases are the leading cause of death, which has been especially...
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