Genes and atherosclerosis: at the origin of the predisposition.

doi:10.1111/j.1368-5031.2005.00439.x

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Article

Genes and atherosclerosis: at the origin of the predisposition.

International journal of clinical practice - 1 Apr 2005

Puddu P, Cravero E, Puddu G M, Muscari A

Abstract excerpt

Atherosclerosis (ATS) is a multifactorial disease caused by the interaction of established or emerging risk factors with multiple predisposing genes that regulate ATS-related processes. This review will discuss the current knowledge concerning the potential role of the genetic variations that could promote and/or accelerate ATS, in both animal models and humans. Allelic polymorphisms or variations of distinct...

Topics

ATP Binding Cassette Transporter 1
ATP-Binding Cassette Transporters
Animals
Arteriosclerosis
Aryldialkylphosphatase
Blood Coagulation
Gene Expression
Genetic Predisposition to Disease
Genotype
Humans
Lipids
Methylenetetrahydrofolate Reductase (NADPH2)
Models, Biological
Mutation
Polymorphism, Genetic
Renin-Angiotensin System
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 15853866
DOI: 10.1111/j.1368-5031.2005.00439.x

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