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Downregulation of miR‑7 and miR‑153 is involved in Helicobacter pylori CagA induced gastric carcinogenesis and progression

24 May 2023

Abstract excerpt

Helicobacter pylori (H. pylori) infection plays a pivotal role in the development of gastric cancer (GC). However, the association between aberrant microRNAs (miRNAs/miRs) expression and H. pylori‑induced GC remains poorly understood. The present study reported that repeated infection of H. pylori caused the oncogenicity of GES‑1 cells in BALB/c Nude mice. miRNA sequencing revealed that both miR‑7 and miR‑153...

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PMID: 37232358
DOI: 10.3892/ijo.2023.5527

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