Article
Impact of pathogen genetics on clinical phenotypes in a population of Talaromyces marneffei from Vietnam.
Genetics - 9 Aug 2023
Sephton-Clark Poppy, Nguyen Thu, Hoa Ngo Thi, Ashton Philip, van Doorn H Rogier, Ly Vo Trieu, Le Thuy, Cuomo Christina A
Abstract excerpt
Talaromycosis, a severe and invasive fungal infection caused by Talaromyces marneffei, is difficult to treat and impacts those living in endemic regions of Southeast Asia, India, and China. While 30% of infections result in mortality, our understanding of the genetic basis of pathogenesis for this fungus is limited. To address this, we apply population genomics and genome-wide association study approaches to a...
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