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Article

KRAS mutations upregulate Runx1 to promote occurrence of head and neck squamous cell carcinoma.

Molecular carcinogenesis - 1 Sept 2023

Deng Miao, Guo Jiaxin, Ling Zihang, Zhang Chi, He Lihong, Fan Zhaona, Cheng Bin, Xia Juan

Abstract excerpt

Gene mutations play an important role in head and neck squamous cell carcinoma (HNSCC) by not only promoting the occurrence and progression of HNSCC but also affecting sensitivity to treatment and prognosis. KRAS is one of the most frequently mutated oncogenes, which has been reported to have a mutation rate from 1.7% to 12.7% and may lead to poor prognosis in HNSCC, but its role remains unclear. Here, we found...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37222390
DOI: 10.1002/mc.23563

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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