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Article

Severe cardiac conduction disease associated with titin gene mutation.

Pacing and clinical electrophysiology : PACE - 1 Feb 2024

Uniat Jonathan, Hill Allison, Shwayder Mark, Bar-Cohen Yaniv

Abstract excerpt

Heart block is rare in pediatrics with many possible causes. An association between complete heart block (CHB) and pathogenic titin (TTN) mutations have not been previously described. We report a 9-year-old female with history of leukodystrophy and family history of atrial fibrillation who presented with syncope and conduction abnormalities, including CHB. She underwent pacemaker implantation and genetic testing...

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Identifiers

PMID: 37221934
DOI: 10.1111/pace.14726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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