Article
Neonatal complex arrhythmias possibly related to a TTN mutation.
Journal of neonatal-perinatal medicine - 1 Jan 2017
Evans William N, Acherman Ruben J, Law Ian H, Von Bergen Nicholas H, Samson Ricardo A, Restrepo Humberto
Abstract excerpt
We describe a neonate born with complex arrhythmias that included concurrent atrial and ventricular tachycardias. Genetic testing demonstrated a mutation in the TTN gene, which codes for titin, a large protein found in striated muscle sarcomeres. The complex arrhythmias were successfully treated with amiodarone and flecainide. The patient remains asymptomatic with normal biventricular function. We speculate that...
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