Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Familial Frequent Premature Ventricular Contractions and the Relevance of Titin Mutations.

Pacing and clinical electrophysiology : PACE - 1 Mar 2026

Hao Yu, An Zhongbin, Wang Haijun, Gao Jinliang, He Ruixia, Ding Yuexin, Ma Guoli, Xu Xinyuan, Qi Bayaer, Liu Xiaoping

Abstract excerpt

BACKGROUND: Pathogenic variants in the Titin gene (TTN) are implicated in a range of cardiac and musculoskeletal disorders. Among these, Titin truncating variants (TTNtv) represent a major genetic cause of dilated cardiomyopathy (DCM) and are frequently associated with various types of arrhythmias. METHODS: We reviewed the medical records of a family presenting with frequent premature ventricular contractions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Connectin

Share to Electrocardiography

Share to Electrocardiography, Ambulatory

Share to TTN gene

Share to Mutation

Share to Pedigree

Source

Identifiers

PMID: 41405006
DOI: 10.1111/pace.70106

Genes

TTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Familial Frequent Premature Ventricular Contractions and the Relevance of Titin Mutations.PMID 41405006Read ↗

A Review of the Giant Protein Titin in Clinical Molecular Diagnostics of CardiomyopathiesSemantic proximity Read ↗

A rising titan: TTN review and mutation update.Semantic proximity Read ↗

Exploring the Familial Phenotypic Variability Associated With TTN Truncating Variants in Cardiomyopathies: Variant Spectrum, Genotype-Phenotype Correlation and Consequences in Genetic Counseling.Semantic proximity Read ↗

Truncations of titin causing dilated cardiomyopathy.Semantic proximity Read ↗

Prevalence and clinical importance of titin truncating variants in adults without known congestive heart failureSemantic proximity Read ↗

Role of titin in cardiomyopathy: from DNA variants to patient stratification.Semantic proximity Read ↗

Genetic epidemiology of titin-truncating variants in the etiology of dilated cardiomyopathySemantic proximity Read ↗

Relevance of Titin Missense and Non-Frameshifting Insertions/Deletions Variants in Dilated CardiomyopathySemantic proximity Read ↗

Novel heterozygous truncating titin variants affecting the A-band are associated with cardiomyopathy and myopathy/muscular dystrophy.Semantic proximity Read ↗

Titin Truncating Variants in Dilated Cardiomyopathy - Prevalence and Genotype-Phenotype Correlations.Semantic proximity Read ↗

Relevance of truncating titin mutations in dilated cardiomyopathy.Semantic proximity Read ↗

A titin truncating variant linked to atrial fibrillation increases atrial profibrotic signalling and cholinergic sensitivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.