Article
The Mutation and Low Expression of ARID1A are Predictive of a Poor Prognosis and High Immune Infiltration in Triple-negative Breast Cancer.
Current cancer drug targets - 1 Jan 2024
Wang Yuejing, Chen Zhuo, Wu Jing, Yan Hong, Wang Yiran, He Jie
Abstract excerpt
BACKGROUND: Triple-negative breast cancer (TNBC) has the poorest prognosis among all breast cancer subtypes. While several tumor types are excepted to have a curative response to immunotherapy through the AT-rich interaction domain 1A (ARID1A) gene, its role in TNBC remains unclear. METHODS: The expression of the ARID1A gene and immune infiltration in TNBC were analyzed by way and function enrichment analysis....
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