Article
Comprehensive analysis of multiple parameters associated with tumor immune microenvironment in ARID1A mutant cancers.
Future oncology (London, England) - 1 Oct 2020
Li Zhenxiang, Lin Jiamao, Zhang Lijuan, Li Jingchao, Zhang Yingyun, Zhao Chenglong, Wang Haiyong
Abstract excerpt
Aim: To verify the relationship between ARID1A and tumor immune microenvironment thus immune checkpoint inhibitors (ICIs) response. Material & methods: Several public databases were used to characterize the association between ARID1A gene alteration and tumor immunity. Results: The gene mutation frequency was 8.2% in all cancer types. The ARID1A-mutated cancers have higher scores of mutation count, tumor...
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