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Article

MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis

27 Apr 2023

Abstract excerpt

Persistent Fusobacterium nucleatum infection is associated with the development of human colorectal cancer (CRC) and promotes tumorigenicity, but the underlying mechanisms remain unclear. Here, we reported that F. nucleatum promoted the tumorigenicity of CRC, which was associated with F. nucleatum -induced microRNA-31 (miR-31) expression in CRC tissues and cells. F. nucleatum infection inhibited autophagic flux...

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PMID: 37216106
DOI: 10.1016/j.isci.2023.106770

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