Simultaneous modeling of multivariate heterogeneous responses and heteroskedasticity via a two-stage composite likelihood.

Abstract excerpt

Multivariate heterogeneous responses and heteroskedasticity have attracted increasing attention in recent years. In genome-wide association studies, effective simultaneous modeling of multiple phenotypes would improve statistical power and interpretability. However, a flexible common modeling system for heterogeneous data types can pose computational difficulties. Here we build upon a previous method for...

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