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Sex and gender as critical and distinct contributors to the human brain-gut-microbiome axis

15 May 2023

Abstract excerpt

The brain-gut-microbiome axis (BGMA) is a pivotal contributor to human health. A large body of research, especially from animal models, has revealed bidirectional, causal relationships between the BGMA and sex. In particular, sex steroids appear to be affected by the BGMA, to influence the BGMA, and to moderate environmental effects on the BGMA. However, animal research on the relationship between sex and the...

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PMID: 37192716
DOI: 10.1016/j.brainresbull.2023.110665

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