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Article

Massive expansion of sex-specific SNPs, transposon-related elements, and neocentromere formation shape the young W-chromosome from the mosquitofish Gambusia affinis.

BMC biology - 15 May 2023

Müller Stefan, Du Kang, Guiguen Yann, Pichler Maria, Nakagawa Shinichi, Stöck Matthias, Schartl Manfred, Lamatsch Dunja K

Abstract excerpt

BACKGROUND: The Western mosquitofish, Gambusia affinis, is a model for sex chromosome organization and evolution of female heterogamety. We previously identified a G. affinis female-specific marker, orthologous to the aminomethyl transferase (amt) gene of the related platyfish (Xiphophorus maculatus). Here, we have analyzed the structure and differentiation of the G. affinis W-chromosome, using a cytogenomics and...

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PMID: 37189152
DOI: 10.1186/s12915-023-01607-0
PMCID: PMC10186657

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