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Article

UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway

1 May 2023

Abstract excerpt

Purpose: Patients with glioblastoma (GBM) have poor prognosis and limited therapeutic options, largely because of chemoresistance to temozolomide (TMZ) treatment. Ubiquitin conjugating enzyme E2 T (UBE2T) plays a key role in regulating the malignancy of various tumors, including GBM; however, its role in TMZ resistance of GBM has not been elucidated. The purpose of this study was to clarify the role of UBE2T in...

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Share to Glioma Diagnosis and Treatment
Share to Microtubule and mitosis dynamics
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37181827
DOI: 10.2147/dddt.s405450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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