Article
Epigenetic age deacceleration in youth at familial risk for schizophrenia and bipolar disorder.
Translational psychiatry - 8 May 2023
Segura Alex G, de la Serna Elena, Sugranyes Gisela, Baeza Inmaculada, Valli Isabel, Díaz-Caneja Covadonga, Martín Nuria, Moreno Dolores M, Gassó Patricia, Rodriguez Natalia, Mas Sergi, Castro-Fornieles Josefina
Abstract excerpt
Epigenetic modifications occur sequentially during the lifespan, but their pace can be altered by external stimuli. The onset of schizophrenia and bipolar disorder is critically modulated by stressors that may alter the epigenetic pattern, a putative signature marker of exposure to environmental risk factors. In this study, we estimated the age-related epigenetic modifications to assess the differences between...
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