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Comparative analyses of bat genomes identify distinct evolution of immunity in Old World fruit bats

5 May 2023

Abstract excerpt

Bats have been identified as natural reservoir hosts of several zoonotic viruses, prompting suggestions that they have unique immunological adaptations. Among bats, Old World fruit bats (Pteropodidae) have been linked to multiple spillovers. To test for lineage-specific molecular adaptations in these bats, we developed a new assembly pipeline to generate a reference-quality genome of the fruit bat Cynopterus...

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PMID: 37146151
DOI: 10.1126/sciadv.add0141

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