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Autophagy‑regulating miRNAs: Novel therapeutic targets for Parkinson's disease (Review)

2 May 2023

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative disorder that has a high incidence during the aging process and is characterized by the loss of dopaminergic neurons in the substantia nigra, leading to motor dysfunctions and non‑motor symptoms. Impaired clearance and excessive accumulation of aberrantly modified proteins or damaged organelles, such as aggregated α‑synuclein and dysfunctional mitochondria, are...

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PMID: 37144489
DOI: 10.3892/ijmm.2023.5253

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