Article
Widespread introgression of MHC genes in Iberian Podarcis lizards.
Molecular ecology - 1 Jul 2023
Gaczorek Tomasz Sebastian, Chechetkin Mateusz, Dudek Katarzyna, Caeiro-Dias Guilherme, Crochet Pierre-André, Geniez Philippe, Pinho Catarina, Babik Wiesław
Abstract excerpt
Major histocompatibility complex (MHC) genes are crucial for the adaptive immune response of jawed vertebrates. Their variation, reaching extreme levels, is driven mainly by an arms race between hosts and pathogens. One hypothesised mechanism contributing to MHC polymorphism is adaptive introgression, the exchange of genetic variants between hybridising species favoured by selection, yet its effect on MHC...
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