Article
Interspecific introgression of MHC genes in Triturus newts: Evidence from multiple contact zones.
Molecular ecology - 1 Feb 2023
Gaczorek Tomasz S, Marszałek Marzena, Dudek Katarzyna, Arntzen Jan W, Wielstra Ben, Babik Wiesław
Abstract excerpt
The major histocompatibility complex (MHC) genes are central to the adaptive immune response in vertebrates. Selection generally maintains high MHC variation because the spectrum of recognized pathogens depends on MHC polymorphism. Novel alleles favoured by selection originate by interallelic recombination or de novo mutations but may also be acquired by introgression from related species. However, the extent and...
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