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Article

Super Enhancer-Associated Circular RNA-CircKrt4 Regulates Hypoxic Pulmonary Artery Endothelial Cell Dysfunction in Mice

4 May 2023

Abstract excerpt

Background: Circular RNAs (circRNAs) have been implicated in pulmonary hypertension progression through largely unknown mechanisms. Pulmonary artery endothelial cell (PAEC) dysfunction is a hallmark in the pathogenesis of pulmonary hypertension. However, the specific role of circular RNAs in PAEC injury caused by hypoxia remains unclear. Methods: In this study, using the Western blotting, RNA pull down,...

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Share to Cardiovascular, Neuropeptides, and Oxidative Stress Research
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PMID: 37139839
DOI: 10.1161/atvbaha.122.318842

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