SARS-CoV-2 variants and mutational patterns: relationship with risk of ventilator-associated pneumonia in critically ill COVID-19 patients in the era of dexamethasone.

doi:10.1038/s41598-023-33639-5

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SARS-CoV-2 variants and mutational patterns: relationship with risk of ventilator-associated pneumonia in critically ill COVID-19 patients in the era of dexamethasone.

Scientific reports - 24 Apr 2023

Razazi Keyvan, Martins Bexiga Anissa, Arrestier Romain, Peiffer Bastien, Voiriot Guillaume, Luyt Charles-Edouard, Urbina Tomas, Mayaux Julien, Pham Tài, Roux Damien, Bellaiche Raphael, AIt Hamou Zakaria, Gaudry Stéphane, Azoulay Elie, Mekontso Dessap Armand, Rodriguez Christophe, Pawlotsky Jean-Michel, Fourati Slim, de Prost Nicolas

Abstract excerpt

We aimed to explore the relationships between specific viral mutations/mutational patterns and ventilator-associated pneumonia (VAP) occurrence in COVID-19 patients admitted in intensive care units between October 1, 2020, and May 30, 2021. Full-length SARS-CoV-2 genomes were sequenced by means of next-generation sequencing. In this prospective multicentre cohort study, 259 patients were included. 222 patients...

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PMID: 37095145
DOI: 10.1038/s41598-023-33639-5
PMCID: PMC10123590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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