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Expression profiles of the CD274 and PLEKHH2 gene and association of its polymorphism with hematologic parameters in sheep.

Veterinary immunology and immunopathology - 1 May 2023

Zhang Yukun, Zhang Xiaoxue, Li Fadi, Lin Changchun, Zhang Deyin, Duan Benzhen, Zhao Yuan, Li Xiaolong, Xu Dan, Cheng Jiangbo, Zhao Liming, Wang Jianghui, Wang Weimin

Abstract excerpt

CD274 and PLEKHH2 genes have been identified as immune- and multiple diseases-related genes, and have recently garnered significant interest. However, their role in regulating immune functions in sheep remains largely unexplored. In this study, we aimed to investigate the effects of polymorphisms in CD274 and PLEKHH2 on hematologic parameters in 915 sheep. Our results showed that the CD274 and PLEKHH2 genes were...

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PMID: 37094535
DOI: 10.1016/j.vetimm.2023.110597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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