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Genomic analysis of worldwide sheep breeds reveals PDGFD as a major target of fat-tail selection in sheep.

BMC genomics - 17 Nov 2020

Dong Kunzhe, Yang Min, Han Jiangang, Ma Qing, Han Jilong, Song Ziyi, Luosang Cuicheng, Gorkhali Neena Amatya, Yang Bohui, He Xiaohong, Ma Yuehui, Jiang Lin

Abstract excerpt

BACKGROUND: Fat tail is a unique trait in sheep acquired during domestication. Several genomic analyses have been conducted in sheep breeds from limited geographic origins to identify the genetic factors underlying this trait. Nevertheless, these studies obtained different candidates. The results of these regional studies were easily biased by the breed structures. RESULTS: To minimize the bias and distinguish...

Topics

Adipose Tissue
Animals
Breeding
Genomics
Platelet-Derived Growth Factor
Polymorphism, Single Nucleotide
Retrospective Studies
Sheep
Tail

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33203382
DOI: 10.1186/s12864-020-07210-9
PMCID: PMC7670677

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