Article
A randomized-controlled trial of SOF/VEL/VOX with or without ribavirin for retreatment of chronic hepatitis C.
Journal of hepatology - 1 Aug 2023
El-Kassas Mohamed, Emadeldeen Mohammed, Hassany Mohamed, Esmat Gamal, Gomaa Ahmed Ali, El-Raey Fathiya, Congly Stephen E, Liu Hongqun, Lee Samuel S
Abstract excerpt
BACKGROUND & AIMS: The combination of sofosbuvir, velpatasvir and voxilaprevir (SOF/VEL/VOX) is recommended for the retreatment of patients with HCV infection in whom previous direct-acting antiviral (DAA) treatment failed. However, whether ribavirin further increases the therapeutic efficacy of SOF/VEL/VOX retreatment remains unclear. We aimed to test this hypothesis in a randomized-controlled trial. METHODS: We...
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