Article
Association between the tumor necrosis factor-alpha -308 G/A gene polymorphism and migraine.
Neurology - 13 Jan 2004
Rainero I, Grimaldi L M E, Salani G, Valfrè W, Rivoiro C, Savi L, Pinessi L
Abstract excerpt
In a group of 299 migraine patients and 306 control subjects, the association of the -308 G/A polymorphism in the tumor necrosis factor-alpha gene (TNFalpha) with the occurrence and clinical characteristics of migraine was tested. Homozygosity for the G allele was associated with an increased risk of migraine (odds ratio [OR] = 2.85, p < 0.001). When the patients were divided into subgroups, the association was...
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