Article
A nodal EBV-positive T cell lymphoma with a T follicular helper cell phenotype.
Histopathology - 1 Jul 2023
Zhang Zhaoxuan, Wang Wei, Li Yuan, Xu Zhouyi, Wu Haibo, Wang Zhe
Abstract excerpt
AIMS: Nodal T follicular helper (TFH) cell lymphoma (nTFHL) is a rare type of clinically aggressive T cell lymphoma. With this lymphoma type, Epstein-Barr virus (EBV) infection is frequently detected in non-neoplastic B lymphocytes, but not yet identified in neoplastic T cells. We report two cases of nTFHL showing a classic morphology and immunoprofile, with EBV-encoded small RNAs (EBER) in-situ hybridisation...
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