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Article

EBV+ nodal T/NK-cell lymphoma associated with clonal hematopoiesis and structural variations of the viral genome.

Blood advances - 14 May 2024

Kato Seiichi, Hamada Motoharu, Okamoto Akinao, Yamashita Daisuke, Miyoshi Hiroaki, Arai Haruto, Satou Akira, Gion Yuka, Sato Yasuharu, Tsuyuki Yuta, Miyata-Takata Tomoko, Takata Katsuyoshi, Asano Naoko, Takahashi Emiko, Ohshima Koichi, Tomita Akihiro, Hosoda Waki, Nakamura Shigeo, Okuno Yusuke

Abstract excerpt

ABSTRACT: Epstein-Barr virus (EBV)-positive (EBV+) nodal T- and natural killer (NK)-cell lymphoma is a peripheral T-cell lymphoma (EBV+ nPTCL) that presents as a primary nodal disease with T-cell phenotype and EBV-harboring tumor cells. To date, the genetic aspect of EBV+ nPTCL has not been fully investigated. In this study, whole-exome and/or whole-genome sequencing was performed on 22 cases of EBV+ nPTCL. TET2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38429084
DOI: 10.1182/bloodadvances.2023012019
PMCID: PMC11068532

Genes

DNMT3A
TET2
RHOA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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