Article
[Familial Mediterranean fever. Immunogenetic and rheumatologic aspects of the disease in a Turkish sibship].
Zeitschrift fur Rheumatologie - 1 Jan 2000
Langer H E, Robin-Winn M, Stangel W, Zeidler H
Abstract excerpt
A family study was performed in 24 members of a Turkish sibship with familial Mediterranean fever (FMF) with 5 patients affected in 3 generations. The well-known autosomal-recessive inheritance of the disease was masked by a pseudodominant appearance, reflecting the striking frequency of congenial marriages. The immunogenetic investigation excluded a linkage between the expression of the disease and the HLA...
Topics
- Adult
- Arthritis, Rheumatoid
- Child
- Familial Mediterranean Fever
- Female
- Genotype
- HLA Antigens
- Humans
- Male
- Middle Aged
- Pedigree
- Turkey
